I think they could run the show for some more time. i know it is tough really to form a new life for Jane after as much he has gone through..but come-on, he is PJ for some reason..he can defeat the odds and arrive in some cool jeans and t-shirt eventually....
           on a more serious note, I think that it is very difficult to make any predictions as it has been left very open ended by the writers..there is even a chance of E=RJ coming back.....so only time could tell..