Bruno Heller once said that Red John is someone like professor Moriarty, a criminal mastermind who created a big nationwide criminal organization. This means that Red John is the founder and the head of the organization "Tyger, Tyger".
Reede Smith can not be Red John because he doesn't seem to be smart enough (apart from all the other missing features). How has he really thought they'll explain about a chained and handcuffed prisoner from the locked trunk of a driving car suddenly ended up fleeing in front of that car on the freeway? And besides, why the prisoner didn't flee into the woods but instead run right down the road? And why did the police officer shot him when he easily could overpower the powerless prisoner? If there's no investigation and implications for Kirkland's death in the upcoming episodes, it would be a huge blunder by the writers!
Regarding the doctor/nurse who showed up at the door of Lisabon's hospital room and asked for Carmen Lee: the name Carmen means "garden" and Lee reversed becomes "eel", thus "garden eel". Perhaps this was an encrypted message to Patrick Jane, e.g. about the secret organization "Tyger, Tyger".
