I don't know if anyone else has mentioned this, but JANE is the female version of JOHN, so the "fearful symmetry" would be for Red John (maybe not Rosalind Harker's boyfriend, but the real mastermind, the "psychic," to be a woman.  Kristina Frye has proposed that she is a "real" psychic to Jane, despite his refutations.  She was able to solve a murder with a seance and make you wonder.  

   She wasn't afraid that RJ would kill her when she went on t.v. -- and she was RIGHT!  She's the first victim, other than Lisbon to escape RJ unscathed, physically.  I have suspected her from the first scene -- seems to smile through her obvious hatred of Patrick.